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10 Best Supplement Affiliate Programs on ClickBank in 2021


If you’re an affiliate marketer looking for great supplements to promote this year, you’re in the right place! In this post, we not only list the best supplement offers out there, but also reveal product commission rates, earnings per click (EPC), average payout value (APV), and links to further resources to help you get started fast!

But first things first: why should you become a supplement affiliate? Well, here at ClickBank, many of the highest-performing products on our marketplace are in the health and fitness supplements industry.

In fact, according to ClickBank’s own internal data, product sales in this niche jumped a staggering 573.4% from 2019 to 2020 – and we routinely see an average payout value in the triple digits for top products on ClickBank. In other words, when you promote a supplement, you can earn an average commission of roughly $100 per sale.

Ready to learn more? Here’s our list of the best supplement affiliate programs to consider on ClickBank so far in 2021 (along with their current YTD numbers).

(And don’t forget, if you want to promote these offers and start making money online, you’ll need a ClickBank account. It’s totally free to join – just sign up here!)

10 Best Supplement Affiliate Programs on ClickBank (Updated Yearly)

1. Biofit

Category: Dietary Supplements
ClickBank Nickname: biofitsupp


EPC = $2.68
APV = $97.15
Starting Commission = 75%
Vendor Contact =

If you regularly view the monthly top products update on ClickBank, then you know that Biofit has topped the list for several months in a row in 2021. This is a dietary supplement for weight loss that comes from a long-time ClickBank Platinum vendor, so you know the product has staying power.

We’re seeing a solid earnings per click (EPC) of $2.00+ for Biofit, and even higher for warm traffic. It’s hard to go wrong with Biofit as an affiliate supplement.

Check out their landing page here.

2. Okinawa Flat Belly Tonic

Category: Diets & Weight Loss
ClickBank Nickname: fbtonic

flat belly tonic

EPC = $1.74
APV = $86.45
Commission = 75%
Affiliate Tools Page =
Vendor Contact =

Flat Belly Tonic continues to be a reliable offer on ClickBank. Where many offers soar for a while and then fizzle, Flat Belly Tonic has managed to remain in the top 10 offers on ClickBank for about a year – which is a huge deal!

One reason Flat Belly Tonic is a good offer is because the people behind it keep optimizing the offer so that it stays fresh. It’s also a unique take on the supplement market (as a tonic instead of a pill). If you want an offer you can get to know and stick with for a while, try Flat Belly Tonic!

Check out their landing page here.

3. Bioptimizers

Category: Dietary Supplements
ClickBank Nickname: bioptimize


EPC = $1.66
APV = $28.62
Commission = 30%
Affiliate Tools Page
= https://bioptimizers.com/affiliate-center/affiliate-center-home/  
Vendor Contact = joey@bioptimizers.com

Here’s another reliable entry in our top 10 products overall for most of 2021. Interestingly, Bioptimzers is more than just a single supplement – it’s actually a product brand offering a number of different quality supplements for sale.

This means you can fully invest in Bioptimzers as a partner in your affiliate business, knowing that they have a variety of health supplements available and aren’t dependent on just one product doing well!

Check out their landing page here.

4. Carbofix

Category: Dietary Supplements
ClickBank Nickname: carbofix


EPC = $1.37
APV = $
Commission = 70%

Vendor Contact = matt@goldvida.com

Carbofix is another top product with incredible staying power. It’s been neck and neck with a few of our other dietary supplement offers throughout 2021, including Biofit – Carbofix even held the record for most sales in one day before Biofit.

This is an offer you can promote for the long term. So far, in spite of a lot of volume being sent to it, Carbofix has maintained great EPC and APV numbers as well. Check it out!

Check out their landing page here.

5. Keravita

Category: Dietary Supplements
ClickBank Nickname: keravita


EPC = $1.49
APV = $96.02
Starting Commission = 65%
Affiliate Tools Page =
Vendor Contact =

Here’s an interesting twist! Unlike many of the weight loss supplements in this top 10 list, Keravita is a unique product formulated to fight toe fungus and promote healthy nails.

Sometimes, focusing on a subniche like this one can help you get more specific in your targeting for better-performing campaigns. If you have an older audience that may need relief from toe fungus, Keravita is a highly successful offer with a high conversion rate and a strong payout of nearly $100 per sale!

Check out their landing page here.

6. Ceracare

Category: Dietary Supplements
ClickBank Nickname: ceracare


EPC = $1.24
APV = $123.70
Starting Commission = 75%
Affiliate Tools Page =
Vendor Contact =

Ceracare contains antioxidants to support healthy blood sugar levels and boost vitality as well. The supplement is equally good for an audience of men or women – but it performs best for an older profile of age 40 or higher.

It also happens to have the highest affiliate payout of any supplement on this list at an astonishing $123.70! Combined with a low refund rate, this makes Ceracare a great product to scale.

Check out their landing page here.

7. Organifi

Category: Dietary Supplements
ClickBank Nickname: organifi


EPC = $1.26
APV = $75.82
Commission = 50%
Affiliate Tools Page = https://www.organifi.com/affiliate-resources/

Vendor Contact = partners@organifi.com

Organifi is a classic ClickBank offer, and easily one of the best and most reliable on our platform. In fact, Organifi is the pioneer of the affiliate supplements category on ClickBank’s marketplace, with a launch of its original Green Juice in September of 2015.

Organifi is still active on ClickBank, with many of its most trusted affiliate partnerships promoting their brand here on our platform. With Organifi’s solid EPC and APV numbers, it’s cloear that Organifi is still a solid contender. Find out more about them through their vendor contact, tools page, or landing page below.

Check out their landing page here.

8. Resurge

Category: Dietary Supplements
ClickBank Nickname: resurge


EPC = $0.50
APV = $95.72
Commission = 75%
Affiliate Tools Page =
Vendor Contact =

Resurge is a sleep and diet supplement first launched in February of 2020, right as the COVID pandemic was starting. The vendor actually faced some shipping and logistics challenges at first, but eventually, Resurge broke through into the upper echelons of the ClickBank marketplace.

This supplement hails from the same partners behind the longest-running #1 product, Venus Factor! With an amazing affiliate payout of nearly $100 and a winning VSL, Resurge is worth a look!

Check out their landing page here.

9. Revision

Category: Dietary Supplements
ClickBank Nickname: revisionus


Revision was an up-and-coming product for a long time, before finally bursting onto the list of top products.

This is another great option targeting a subniche (in this case, eye health). With a 75% commission and payout nearing $100, Revision is definitely a good option – and probably has less competition than some of the most popular supplement offers!

EPC = $1.32
APV = $95.72
Commission = 75%
Affiliate Tools Page =
Vendor Contact =

Check out their landing page here.

10. Toxiburn

Category: Dietary Supplements
ClickBank Nickname: toxib209


EPC = $1.36
APV = $111.32
Commission = 75%
Affiliate Tools Page =
Vendor Contact =

Toxiburn is a rising star that’s still burning hot on ClickBank right now. What’s impressive is how well it’s competing with some of our other health and fitness mainstays, even without a long track record.

It’s converting well on all the usual platforms like Facebook and Instagram, but even seeing results on Pinterest! With an incredible APV of more than $111, you’ve got to give this one a look!

Check out their landing page here.

Frequently Asked Questions

Is the supplement affiliate niche worth doing?

As a general rule, yes! Health and fitness offers will always be in demand, and supplements are particularly hot right now. We’re also seeing some $100+ payout values, so you can expect a solid ROI from supplement products on ClickBank.

With that said, it’s a highly competitive space and you need to have a solid grasp on your audience to succeed here. Just like with most things, you’ll be more successful if you have passion and expertise in the supplement affiliate niche.

Which supplement affiliate program is the best?

At ClickBank, we track affiliate marketing trends, and we’ve seen the market for supplements grow by leaps and bounds in the last few years. That means you can’t really go wrong if you’re picking a supplement offer from this list.

However, it’s still important to do your own research and find the one that works best for your audience. And you should also remember that even the best-performing offers can lose their luster if the market gets oversaturated with them. That’s why it’s sometimes a good idea to focus on the trending or up-and-coming products that the biggest affiliates and media buyers aren’t focused on yet.

How do I get started as a supplement affiliate?

From BioFit to Toxiburn, these are all great supplements for affiliates to promote, but the question is how to get started as a supplement affiliate!

Fortunately, ClickBank offers a lot of great resources to help you, including this guide to free traffic – but here is a quick primer on the main approaches you can take!

Paid Traffic

I have to be honest – a lot of the top ClickBank health and fitness affiliates are media buyers relying on paid traffic through platforms like Facebook or Google. They make money by creating compelling ads that drive cold traffic to these landing pages (sometimes with an affiliate bridge page in between), and because the average payout values are often $100 a pop, they can afford to spend a lot on ads and still see a nice profit.

Paid traffic is going to give you the quickest return, but it also requires a lot more of an upfront investment.


YouTube is a good middle-of-the-road approach to making money with health supplements. You can create content centered around a particular audience – such as older women or young athletes – and then include helpful content with an affiliate link in the description. This is a huge opportunity, but to get the best results, you’ll need to regularly deliver valuable content and establish real trust with your audience.

SEO Affiliate Site

One more opportunity to grow your affiliate supplement business is by building an affiliate website dedicated to the subject. Just like with YouTube, you’ll want to focus on audience building here, generally either focused around your niche or around a certain audience segment. (For example, “ankle pain” or “Moms Over 40”.) SEO is a longer-term play than YouTube, as it can be difficult to get traction in search engines like Google without serious time and effort on everything from content creation to link building.

Of course, as you grow your affiliate business, you’ll probably want to have all three, as each one offers its own advantages and disadvantages. I would also encourage affiliate email marketing – building an email list is one of the best ways to ensure a sustainable affiliate business.

Conclusion: Best Affiliate Supplement Programs on Clickbank

There’s honestly never been a better time to get in on the supplement affiliate niche. In the emerging post-COVID world, people are more focused than ever on their health, so it’s worthwhile to help get these quality wellness products into the hands of people who need them!

Of course, while these are the 10 best supplement affiliate programs on ClickBank right now, things can (and do) change! We’ll be updating this post every year, but if you want to see which products performing best on ClickBank each month overall, be sure to check out our top ClickBank products post and see what’s trending – you can also subscribe to our YouTube channel to keep up-to-date with our top offers updates.

Lastly, if If you don’t already have a ClickBank account, it’s free to sign up! Just head over to the ClickBank sign up page to get started! You’ll need an account to generate a HopLink you can promote to start making money online.

Lastly, be sure to check out the official ClickBank Spark Certification course. This walks you through everything you need to know to start promoting or selling offers like these quality affiliate supplements.

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